Polymer-based fluorophores provide remarkably bright readouts for better differentiation of cell subpopulations in a flow cytometry workflow. However, because of their inherent nature, they tend to interact with each other and form aggregates. It is difficult to dry down panels containing two or more polymer-based fluorophores, and even liquid cocktails require a specialized buffer to prevent. non-specific interactions. Beckman Coulter Life Sciences, known for its DURA (Dry Unitized Reagents Assay) Innovations products, has developed a breakthrough technology enabling the dry down of multiple bright polymer SuperNova dyes in the same tube along with other conventional dyes (FITC, PE, ECD, etc.). The proprietary technology prevents any non-specific interactions between the polymer dyes and does not require the addition of any specialized stain buffers. The novel technology can also be used to dry down antibodies for intracellular markers, beads, and viability dyes. The panel performance shows good results without any nonspecific interaction when compared to other competitors' conjugates. This technology allows users to extend the application of multicolor panels with a novel range of polymer dyes.